Portfolio

Livio Radio

www.livioradio.com

Based in: Ferndale, Mich.
Sector: Consumer Products
Date Invested: June 2010

Founded in 2008, Livio Radio aims to make Internet audio streams accessible to more people, in more places. Dedicated to designing products that work fast without complicated menus, the company’s line of specialty radios, including the NPR Radio by Livio and the Livio Radio featuring Pandora, let users enjoy the benefits of online programming — music, sports, news and talk from around the world — anywhere an Internet connection is available. The Livio Car Internet Radio App for iPhone uses a high-speed data connection and a streamlined interface to offer the thousands of free online programming choices, along with traditional AM/FM radio broadcasts, for users on the go. Visit www.livioradio.com for more information.

Liberty Dialysis

www.libertydialysis.com

Based in: Detroit, Mich.
Sector: Healthcare
Date Invested: May 2010

Liberty Dialysis develops, owns and operates dialysis clinics throughout the United States, particularly in underserved communities. The company partners with local physicians, nephrologists, non-profit organizations and/or hospitals in owning and operating the centers.

Delphinus Medical Technologies

www.delphinusmt.com

Based in: Detroit, Mich.
Sector: Healthcare
Date Invested: May 2010

Delphinus Medical Technologies, a spinout from the Barbara Ann Karmanos Cancer Institute in Detroit, is the developer of SoftVue, an alternative to mammography for breast cancer detection, risk evaluation and treatment monitoring.

The SoftVue system does not involve radiation or compression and can effectively differentiate benign from malignant masses in breasts, helping to reduce the number of false positives and thereby reduce unnecessary biopsies. Unlike mammography the breast is submerged in warm water and an ultrasound ring surrounds the breast and captures detailed, three-dimensional images through the use of sound waves. The results are similar to MRI; however the SoftVue system takes only minutes and costs much less. The system is also able to perform repeated imaging, a necessary tool for treatment monitoring.

In addition, through its three-dimensional capabilities, SoftVue can accurately measure breast density, a known risk factor for developing breast cancer, as well as detect many early stages of breast cancer in women with dense breast tissue, which is often not picked up by mammography.

InTouch Health

www.intouchhealth.com

Based in: Michigan-based engineering R&D center currently under expansion
Sector: Healthcare
Date Invested: April 2010

InTouch Health provides comprehensive telemedicine solutions that enable physicians to remotely perform real-time consults with hospital patients. Through a single interface, physicians can access a host of FDA-cleared Remote Presence devices to provide and document care into emergency rooms, critical care units, patient wards and operating rooms. Wherever access to medical expertise is limited, InTouch Health’s Remote Presence telemedicine solutions can effectively extend the physician’s reach to manage patient care, thereby removing critical time and distance barriers.

The Company has more than 300 hospital locations on six continents using Remote Presence to deliver specialty care services such as stroke, cardiology, trauma, pediatrics, neonatology, psychiatry, translation services, critical care coverage, patient rounds, clinical education, and surgical/procedure mentoring.

Sakti3, Inc.

www.sakti3.com

Based in: Ann Arbor, Mich.
Sector: Clean Technology
Date Invested: March 2010

Sakti3 is a developer of high performance solid state lithium-ion rechargeable batteries for electric vehicles and portable electronics. The company’s modeling, manufacturing process and initial production batteries have proven at a small scale that it has strong potential to produce batteries that radically change the performance and economics of electrified vehicles.

Founded in 2007, Sakti3 is a spin-out of the University of Michigan. In 2009, the company was designated by the Michigan Economic Development Corporation (MEDC) as a State of Michigan Center of Energy Excellence (CoEE) in partnership with the University of Michigan.

Relume Technologies

www.relume.com

Based in: Oxford, Mich.
Sector: Clean Technology
Date Invested: December 2009

Relume Technologies designs, manufacturers and markets highly efficient, environmentally friendly and cost effective LED lighting products and smart-grid control systems for outdoor lighting applications. The company’s products are used primarily in street and area lighting for municipalities and corporations, commercial signage, outdoor advertising, transportation and U.S. military applications.

Relume’s patented thermal management technology enables its LEDs to burn brighter, last longer and be packaged in lighting fixtures that cost less. The company’s smart-grid technology, Sentinel™, allows municipalities, counties and departments of transportation to network their LED-based light fixtures (including those of competitors) and incumbent lighting technologies to remotely control them to power up or dim lights across all or parts of the network, reducing energy consumption, maintenance costs and CO₂ generation.

Accuri Cytometers

www.accuricytometers.com

Based in: Ann Arbor, Mich.
Sector: Life Sciences
Date Invested: July 2009

Accuri Cytometers, Inc. is a life sciences company developing and marketing revolutionary high performance cell analysis systems designed to bring the power of flow cytometry into the labs of life science researchers everywhere. Reflecting the input of hundreds of researchers, the Accuri C6 Flow Cytometer(R) is a full-featured bench-top cell and bead analysis system that provides similar capabilities to those of industry-leading flow cytometers in an easy-to-use format and at a fraction of their cost. The Accuri system was engineered from the start to be compact, powerful and user-friendly, while also being affordable by most research laboratories. The Accuri CSampler(TM) adds simple, reliable and user-friendly automation to the Accuri C6 Flow Cytometer System.

Inland Pipe Rehabilitation

www.inlandpiperehab.com

Based in: Detroit, Mich.
Sector: Industrial Products
Date Invested: June 2009

Inland Pipe Rehabilitation (IPR) is an experienced, nationwide provider of trenchless repair and rehabilitation solutions for water, sewer, manhole and culvert applications. The company uses the industry’s leading trenchless technologies including pipe bursting, CIPP and Rib Loc. IPR has successfully rehabilitated over one million feet of pipe for both public and private sector clients across the United States.

Hearthside Food Solutions

www.hearthsidefoods.com

Based in: Grand Rapids, Mich.
Sector: Consumer Products
Date Invested: May 2009

Hearthside Food Solutions, is a leading contract manufacturer of specialty food products, such as granola bars, croutons, cereals, popcorn, and snack mixes, that supplies North America’s leading consumer product companies.

gloStream

www.glostream.com

Based in: Bloomfield Hills, Mich.
Sector: Healthcare Information Technology
Date Invested: May 2009

gloStream provides physicians and healthcare facilities with electronic medical record and practice management solutions delivered and supported through a nationwide network of local technology partners. gloStream products are secure, easy-to-use applications and the only integrated EMR/PM solutions on the market embedded with Microsoft Office. Through a simple user interface, robust voice recognition technology, and single-click access to all patient information, gloStream products help doctors improve patient care by streamlining workflow and creating efficiencies in office administration. gloEMR™ version 4.0 from gloStream is a CCHIT Certified℠ product for CCHIT Ambulatory EHR 2007.

Ranir

www.ranir.com

Based in: Grand Rapids, Mich.
Sector: Consumer Products
Date Invested: April 2009

Ranir manufactures and markets consumer oral care products in North America. It offers manual and power toothbrushes, dental floss and flossers, night protectors, tooth whiteners, trial-sized products, travel kits, and other oral care accessories to retailers as private label products as well as to contract manufacturing customers as branded products.

Pioneer Surgical Technology

www.pioneersurgical.com

Based in: Marquette, Mich.
Sector: Medical Device Manufacturing
Date Invested: December 2008

Pioneer Surgical Technology, Inc., headquartered in Marquette, Michigan, is a dynamic medical device firm with a full line of cutting-edge motion preservation devices, either available commercially in Europe or under clinical evaluation in the U.S. Pioneer’s signature articulating P3™ Technology — Pioneer PEEK-on-PEEK, in its NuBac™ disc arthroplasty system, BacJac™ interspinous decompression system, and NuNec™ artificial cervical disc, is the most technologically advanced in the industry. Currently, Pioneer offers a diverse portfolio of next generation spinal fusion devices. Pioneer’s focus on innovation has resulted in over 100 U.S. and Foreign patents with numerous patents pending. The company established a Biologics Division following two acquisitions in 2007. Pioneer Orthobiologics is developing a rich pipeline of products indicated for a variety of spinal and orthopaedic applications. Pioneer focuses on developing products which are easier and faster for the surgeon, cost effective for the health care system, and provide better patient outcomes.

EcoSynthetix

www.ecosynthetix.com

Based in: Lansing, Mich.
Sector: Clean Technology
Date Invested: November 2008

EcoSynthetix Inc., established in 1996, specializes in the R&D, process scale-up, manufacturing and commercialization of biobased technologies. The EcoSynthetix technology platforms are best described as clean technologies because they provide biobased products derived from renewable resources that have a positive impact on the environment. The renewable raw material feedstocks significantly reduce North America’s dependence on foreign-based fossil fuels, and reduce the end-user’s carbon footprint. The Company’s biopolymer nanoparticle technology platform provides EcoSphere® biolatex products as replacements for petroleum-based paper and paperboard coating binders such as SB and SA Latex. At substitution levels up to 50%, the biolatex products are comparable or superior to traditional petroleum-based alternatives and can be specifically formulated to deliver previously unattainable benefits at a lower delivered cost to industrial users.

In addition, the Company has developed EcoMer®, a polymerizable sugar monomer, and a line of EcoStix® sugar-acrylic PSA (pressure sensitive adhesive) products for label and specialty adhesives applications.